Pent-4-enylmagnesium bromide, 0.50 M in THF - Introduction
4-penten-1-ylmagnesium bromide is an organic compound with the chemical formula C5H9BrMg. It is an organolithium reagent made by the reaction of pentene and magnesium. Its properties are as follows:
1. Appearance: colorless liquid or crystalline solid;
2. Solubility: Soluble in cyclohexane, ether and benzene and other organic solvents;
3. Stability: sensitive to air and water, should be stored and operated in an inert atmosphere.
4-penten-1-ylmagnesium bromide is mainly used for Grignard reagent in organic synthesis reaction. Common applications include:
1. hydroxylation reaction: reaction with acids to generate alcohol;
2. Carboxylation reaction: reacting with acids to generate carboxylic acids;
3. carbon-carbon bond formation reaction: reaction with aldehydes or ketones to generate alcohols.
The method for preparing 4-penten-1-ylmagnesium bromide in the laboratory is to react pentene with magnesium bromide. The reaction temperature and reaction time need to be controlled during the reaction. The preparation process needs to pay attention to safety, should be operated under the condition of protective gloves and goggles, and pay attention to proper ventilation and protective measures.
Since 4-penten-1-ylmagnesium bromide is an organic magnesium reagent, it has a violent reaction with air and water, so be careful during operation. It should be operated under protective facilities, away from fire and heat sources. In addition, contact with acids, oxidants or other organics should be avoided to prevent dangerous reactions.
This is an introduction to the nature, use, formulation and safety information of the 4-penten-1-ylmagnesium bromide. In different applications, it is also necessary to carry out operation and risk assessment according to the reaction conditions and requirements.